02/08/20 Fatigue day?

I think yesterday was my "fatigue" day for this week. I don't like calling it that because I understand that all-out fatigue goes way beyond what I get, but equally it goes beyond just feeling tired. I'm getting an instinct - without any supporting evidence - that it's a reaction to the falling dex level three or four days after taking it. And if that's right, the reason why I didn't get the same thing when I was on double the dose (over two days) is that the dex level never dropped low enough. Maybe I could try splitting the current 20mg on  one day into 2 x 10mg over two days? Something to talk to Dr.Ch about next time. Before then I'll try to do a little research on the point.

Some quick Googling suggests this may be right. Dex fatigue a few days after taking it tends to increase with prolonged use of dex, and the combination with Revlemid / Lenalidomide (also a cause of fatigue by itself at higher doses such as my 25mg daily) can increase the effect. Well, I'm halfway through Cycle 3 of the current consolidation program and the last week of that is off Len. And after Cycle 4 I'll be off dex altogether (that's Sep.16th, if I've worked it out right) but staying on low-dose Len. I can stand a touch of fatigue for that long, especially if I know it's coming.